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Article

Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation.

Neuro-degenerative diseases - 1 Jan 2011

Bellucci Arianna, Bugiani Orso, Ghetti Bernardino, Spillantini Maria Grazia

Abstract excerpt

BACKGROUND: Recent findings, showing the presence of an inflammatory process in the brain of transgenic mice expressing P301S mutated human tau protein, indicate that neuroinflammation may contribute to tau-related degeneration in frontotemporal dementia and parkinsonism linked to chromosome 17 with tau mutations (FTDP-17T). OBJECTIVE: To investigate the occurrence of neuroinflammatory changes in the brain of a...

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Identifiers

PMID: 21212632
DOI: 10.1159/000322228
PMCID: PMC3214942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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