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Article

Activating mutations of TOR (target of rapamycin).

Genes to cells : devoted to molecular & cellular mechanisms - 1 Feb 2011

Hardt Molly, Chantaravisoot Naphat, Tamanoi Fuyuhiko

Abstract excerpt

Mammalian target of rapamycin (mTOR) is a key regulator of eukaryotic cell growth. In particular, mTORC1, one of the two complexes that contain mTOR, is involved in the regulation of protein synthesis, proliferation, cell cycle and autophagy. Hyperactivation of the mTOR signaling pathway is obser...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21210909
DOI: 10.1111/j.1365-2443.2010.01482.x
PMCID: PMC3116645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21210909-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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