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Article

Ablation of renin-expressing juxtaglomerular cells results in a distinct kidney phenotype.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Mar 2004

Pentz Ellen Steward, Moyano Maria Alejandra, Thornhill Barbara A, Sequeira Lopez Maria Luisa S, Gomez R Ariel

Abstract excerpt

Renin-expressing cells are peculiar in that they act as differentiated cells, producing the hormone renin, while they also seem to act as progenitors for other renal cell types. As such, they may have functions independent of their ability to generate renin/angiotensin. To test this hypothesis, we ablated renin-expressing cells during development by placing diphtheria toxin A chain (DTA) under control of the...

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Identifiers

PMID: 14563659
DOI: 10.1152/ajpregu.00426.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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