Article
The recent breakthroughs in the understanding of host genomics in hepatitis C.
European journal of clinical investigation - 1 Oct 2010
Rauch Andri, Rohrbach Janine, Bochud Pierre-Yves
Abstract excerpt
BACKGROUND: Hepatitis C Virus (HCV) infection is spontaneously resolved in about 30% of acutely infected individuals. In those who progress to chronic hepatitis C, HCV therapy permanently eradicates infection in about 40% of cases. It has long been suspected that host genetic factors are key determinants for the control of HCV infection. DESIGN: We will review in this study four genome-wide association studies...
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