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Molecular and cellular bases of chronic myeloid leukemia

1 Feb 2010

Abstract excerpt

Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by the overproduction of granulocytes, which leads to high white blood cell counts and splenomegaly in patients. Based on clinical symptoms and laboratory findings, CML is classified into three clinical phases, often starting with a chronic phase, progressing to an accelerated phase and ultimately ending in a terminal phase called blast...

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PMID: 21203982
DOI: 10.1007/s13238-010-0016-z

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