Article
Spontaneous deletion formation within the beta-galactosidase gene of Lactobacillus bulgaricus.
Journal of bacteriology - 1 Oct 1990
Mollet B, Delley M
Abstract excerpt
To investigate the genetic stability of the dairy organism Lactobacillus bulgaricus, we have analyzed 107 spontaneous mutations of the beta-galactosidase gene of this organism. Ten of these mutations were DNA rearrangements giving rise to different deletions, located predominantly within a small hot spot area. The DNA sequences of the different deletion junctions have been determined. The analysis showed that the...
Topics
- Base Sequence
- Chromosome Deletion
- DNA, Bacterial
- Genes, Bacterial
- Lactobacillus
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Oligonucleotide Probes
- Plasmids
