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Article

Structural analysis of the transcriptional activation region on Fis: crystal structures of six Fis mutants with different activation properties.

Journal of molecular biology - 6 Oct 2000

Cheng Y S, Yang W Z, Johnson R C, Yuan H S

Abstract excerpt

The Fis protein regulates gene expression in Escherichia coli by activating or repressing transcription of a variety of genes. Fis can activate transcription when bound to DNA upstream of the RNA-polymerase-binding site, such as in the rrnB P1 promoter, or when bound to a site overlapping the -35 RNA polymerase binding site, such as in the proP P2 promoter. It has been suggested that transcriptional activation in...

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Identifiers

PMID: 11183780
DOI: 10.1006/jmbi.2000.4123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural analysis of the transcriptional activation region on Fis: crystal structures of six Fis mutants with different activation properties.PMID 11183780Read ↗

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