Article
The source matters: no impact of the CCL2/MCP-1-1-2518G polymorphism of the donor on renal allograft outcome during the first year after transplantation.
Transplantation proceedings - 1 Dec 2008
Lehmann I, Fischereder M, Böhmig G A, Regele H, Exner M, Raith M, Weiss N, Segerer S
Abstract excerpt
Chemokines are involved in the recruitment of inflammatory cells to vascularized allografts. The chemokine CCL2/MCP-1 is expressed during allograft dysfunction, which is associated with the recruitment of inflammatory cells. Both intrinsic renal cells (donor origin) as well as infiltrating inflammatory cells (recipient origin) can be a source of CCL2/MCP-1. We previously demonstrated that the recipient...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.