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Article

Molecular evolution, mutation size and gene pleiotropy: a geometric reexamination.

Genetics - 1 Mar 2011

Razeto-Barry Pablo, Díaz Javier, Cotoras Darko, Vásquez Rodrigo A

Abstract excerpt

The influence of phenotypic effects of genetic mutations on molecular evolution is not well understood. Neutral and nearly neutral theories of molecular evolution predict a negative relationship between the evolutionary rate of proteins and their functional importance; nevertheless empirical studies seeking relationships between evolutionary rate and the phenotypic role of proteins have not produced conclusive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21196522
DOI: 10.1534/genetics.110.125195
PMCID: PMC3048784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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