Article
Interaction between mutation type and gene pleiotropy drives parallel evolution in the laboratory.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 22 May 2023
Ruelens Philip, Wynands Thomas, de Visser J Arjan G M
Abstract excerpt
What causes evolution to be repeatable is a fundamental question in evolutionary biology. Pleiotropy, i.e. the effect of an allele on multiple traits, is thought to enhance repeatability by constraining the number of available beneficial mutations. Additionally, pleiotropy may promote repeatability by allowing large fitness benefits of single mutations via adaptive combinations of phenotypic effects. Yet, this...
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