Article
Polymorphisms in MMP-9 and TIMP-2 in Chinese patients with varicose veins.
The Journal of surgical research - 1 Jun 2011
Xu Hong-mei, Zhao Yun, Zhang Xiang-man, Zhu Ting, Fu Wei-guo
Abstract excerpt
BACKGROUND: Varicose veins (VVs), a common vascular disease, are functionally characterized by dilation and tortuosity and are widely prevalent in the adult population. The pathophysiology and molecular mechanism of VVs are still unclear. A genetic risk for VVs has been demonstrated, although no genetic variant pertaining to VVs has been identified. Matrix metalloproteinases (MMPs) and their endogenous tissue...
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