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Article

Genetic polymorphisms of vein wall remodeling in chronic venous disease: a narrative and systematic review.

Blood - 21 Aug 2014

Bharath Vighnesh, Kahn Susan R, Lazo-Langner Alejandro

Abstract excerpt

Chronic venous disease encompasses a spectrum of disorders caused by an abnormal venous system. They include chronic venous insufficiency, varicose veins, lipodermatosclerosis, postthrombotic syndrome, and venous ulceration. Some evidence suggests a genetic predisposition to chronic venous disease from gene polymorphisms associated mainly with vein wall remodeling. The literature exploring these polymorphisms has...

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Identifiers

PMID: 25006132
DOI: 10.1182/blood-2014-03-558478

Genes

FOXC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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