Article
MMP2 gene polymorphisms and MMP2 mRNA levels in patients with superficial varices of lower extremities.
In vivo (Athens, Greece) - 1 Jan 2000
Görmüş Uzay, Kahraman Ozlem Timirci, Isbir Selim, Tekeli Atike, Isbir Turgay
Abstract excerpt
BACKGROUND: Although superficial varices of lower extremities with high morbidity are common, their etiology has not been elucidated yet. Previously, it was thought that venous hypertension was responsible for such cases by causing valvular insufficiency, but recent findings indicate that the changes in the venous wall structure might be main initiating factors. Matrix metalloproteinase enzyme-2 (MMP2) is one of...
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