Article
White blood cell count at diagnosis and immunoglobulin variable region gene mutations are independent predictors of treatment-free survival in young patients with stage A chronic lymphocytic leukemia.
Haematologica - 1 Apr 2011
Del Giudice Ilaria, Mauro Francesca Romana, De Propris Maria Stefania, Santangelo Simona, Marinelli Marilisa, Peragine Nadia, Di Maio Valeria, Nanni Mauro, Barzotti Rita, Mancini Francesca, Armiento Daniele, Paoloni Francesca, Guarini Anna, Foà Robin
Abstract excerpt
A comprehensive panel of clinical-biological parameters was prospectively evaluated at presentation in 112 patients with chronic lymphocytic leukemia (<65 years), to predict the risk of progression in early stage disease. Eighty-one percent were in Binet stage A, 19% in stages B/C. Treatment-free survival was evaluated as the time from diagnosis to first treatment, death or last follow up. In univariate analysis,...
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