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Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia

25 Jul 2007

Abstract excerpt

Several parameters may predict disease severity and overall survival in chronic lymphocytic leukemia (CLL). The purpose of our study of 190 CLL patients was to compare immunoglobulin heavy chain variable region (IgV(H)) mutation status, cytogenetic abnormalities, and leukemia cell CD38 and Zap-70 to older, traditional parameters. We also wanted to construct a simple, inexpensive prognosis score that would...

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PMID: 17654680
DOI: 10.1002/ajh.20987

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