Article
IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia.
Journal of translational medicine - 30 Jan 2012
Bulian Pietro, Rossi Davide, Forconi Francesco, Del Poeta Giovanni, Bertoni Francesco, Zucca Emanuele, Montillo Marco, Pozzato Gabriele, D'Arena Giovanni, Efremov Dimitar G, Marasca Roberto, Lauria Francesco, Gaidano Gianluca, Gattei Valter, Laurenti Luca
Abstract excerpt
BACKGROUND: Prognostic index for survival estimation by clinical-demographic variables were previously proposed in chronic lymphocytic leukemia (CLL) patients. Our objective was to test in a large retrospective cohort of CLL patients the prognostic power of biological and clinical-demographic variable in a comprehensive multivariate model. A new prognostic index was proposed. METHODS: Overall survival and time to...
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