Article
Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait?
European journal of haematology - 1 May 2022
Brieghel Christian, Galle Veerle, Agius Rudi, da Cunha-Bang Caspar, Andersen Michael A, Vlummens Philip, Mattsson Mattias, Rosenquist Richard, Smedby Karin E, Herling Carmen D, Bahlo Jasmin, Hallek Michael, Lundgren Jens D, Offner Fritz, Niemann Carsten U
Abstract excerpt
INTRODUCTION: Early-stage chronic lymphocytic leukemia (CLL) challenges specialized management and follow-up. METHODS: We developed and validated a prognostic index to identify newly diagnosed patients without need of treatment (CLL-WONT) by a training/validation approach using data on 4708 patients. Composite scores derived from weighted hazards by multivariable analysis defined CLL-WONT risk groups. RESULTS:...
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