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Article

Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice.

PloS one - 20 Dec 2010

Li Dejia, Yue Yongping, Duan Dongsheng

Abstract excerpt

Inactivation of all utrophin isoforms in dystrophin-deficient mdx mice results in a strain of utrophin knockout mdx (uko/mdx) mice. Uko/mdx mice display severe clinical symptoms and die prematurely as in Duchenne muscular dystrophy (DMD) patients. Here we tested the hypothesis that marginal level...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21187970
DOI: 10.1371/journal.pone.0015286
PMCID: PMC3004926

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21187970-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice.PMID 21187970Read ↗

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