Article
Functional consequences of natural sequence variation of murine cytomegalovirus m157 for Ly49 receptor specificity and NK cell activation.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2011
Corbett Alexandra J, Coudert Jerome D, Forbes Catherine A, Scalzo Anthony A
Abstract excerpt
The Ly49H activating receptor on C57BL/6 (B6) NK cells plays a key role in early resistance to murine cytomegalovirus (MCMV) infection through specific recognition of the MCMV-encoded MHC class I-like molecule m157 expressed on infected cells. The m157 molecule is also recognized by the Ly49I inh...
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