Article
Characterization of murine cytomegalovirus m157 from infected cells and identification of critical residues mediating recognition by the NK cell receptor Ly49H.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2008
Davis Aja H, Guseva Natalya V, Ball Brianne L, Heusel Jonathan W
Abstract excerpt
Activated NK cells mediate potent cytolytic and secretory effector functions and are vital components of the early antiviral immune response. NK cell activities are regulated by the assortment of inhibitory receptors that recognize MHC class I ligands expressed on healthy cells and activating receptors that recognize inducible host ligands or ligands that are not well characterized. The activating Ly49H receptor...
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