Article
Analysis of T cell receptor beta and gamma genes from peripheral blood, regional lymph node and tumor-infiltrating lymphocyte clones from melanoma patients.
Cancer immunology, immunotherapy : CII - 1 Jan 1991
Albertini M R, Nicklas J A, Chastenay B F, Hunter T C, Albertini R J, Clark S S, Hank J A, Sondel P M
Abstract excerpt
A total of 199 T cell clones from two melanoma patients were derived from progenitor T cells from recurrent melanoma, regional lymph nodes (either involved or uninvolved with malignancy) and peripheral blood by inoculating single cells directly into the wells of microtiter plates before in vitro...
Topics
- Adult
- Blotting, Southern
- CD4 Antigens
- Cells, Cultured
- DNA Probes
- Humans
- Lymph Nodes
- Lymphocyte Activation
- Lymphocyte Subsets
- Lymphocytes
- Lymphocytes, Tumor-Infiltrating
- Male
- Melanoma
- Middle Aged