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Article

Clonal expansions of 6-thioguanine resistant T lymphocytes in the blood and tumor of melanoma patients.

Environmental and molecular mutagenesis - 1 Dec 2008

Albertini Mark R, Macklin Michael D, Zuleger Cindy L, Newton Michael A, Judice Stephen A, Albertini Richard J

Abstract excerpt

The identification of specific lymphocyte populations that mediate tumor immune responses is required for elucidating the mechanisms underlying these responses and facilitating therapeutic interventions in humans with cancer. To this end, mutant hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficient (HPRT-) T-cells were used as probes to detect T-cell clonal amplifications and trafficking in vivo in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18712786
DOI: 10.1002/em.20417
PMCID: PMC3037545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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