Article
Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma.
World journal of gastroenterology - 28 Dec 2010
Zhao Jing, Yu Bing-Yun, Wang Dao-Yuan, Yang Jin-E
Abstract excerpt
AIM: to investigate the effect of the G-1666A polymorphism in the multidrug resistance related protein-1 (MRP1) on outcome of hepatocellular carcinoma (HCC). METHODS: a cohort of 162 patients with surgically resected HCC who received no postsurgical treatment until relapse was studied. Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism analysis. Electrophoretic mobility...
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