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Association analysis between MDR1 gene polymorphisms and risk of hepatocellular carcinoma in Chinese population.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 May 2013

Yang Daokun, Zhou Fujun, Wang Xinwei, Gao Haili, Li Guangyan, Xue Minghui

Abstract excerpt

The objective of this study was to evaluate the association between MDR1 gene polymorphisms and hepatocellular carcinoma (HCC) risk. Genomic DNA of 1431 subjects was extracted from peripheral blood and genotyping was performed using the created restriction site-polymerase chain reaction (CRS-PCR). We found that the c.1465C > T single nucleotide polymorphisms (SNP) increased HCC risk in all genetic models (p <...

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PMID: 23488625
DOI: 10.3109/1354750X.2013.773079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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