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Article

The neurotoxicity of DOPAL: behavioral and stereological evidence for its role in Parkinson disease pathogenesis.

PloS one - 13 Dec 2010

Panneton W Michael, Kumar V B, Gan Qi, Burke William J, Galvin James E

Abstract excerpt

BACKGROUND: The etiology of Parkinson disease (PD) has yet to be fully elucidated. We examined the consequences of injections of 3,4-dihydroxyphenylacetaldehyde (DOPAL), a toxic metabolite of dopamine, into the substantia nigra of rats on motor behavior and neuronal survival. METHODS/PRINCIPAL FI...

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Identifiers

PMID: 21179455
DOI: 10.1371/journal.pone.0015251
PMCID: PMC3001493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21179455-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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