Article
Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid.
PloS one - 17 Dec 2010
Lu Ling, Zhou Xiaohui, Wang Julie, Zheng Song Guo, Horwitz David A
Abstract excerpt
BACKGROUND: Protective CD4+CD25+ regulatory T cells bearing the Forkhead Foxp3 transcription factor can now be divided into three subsets: Endogenous thymus-derived cells, those induced in the periphery, and another subset induced ex-vivo with pharmacological amounts of IL-2 and TGF-β. Unfortunat...
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