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Article

Mechanism of chloride interaction with neurotransmitter:sodium symporters.

Nature - 11 Oct 2007

Zomot Elia, Bendahan Annie, Quick Matthias, Zhao Yongfang, Javitch Jonathan A, Kanner Baruch I

Abstract excerpt

Neurotransmitter:sodium symporters (NSS) have a critical role in regulating neurotransmission and are targets for psychostimulants, anti-depressants and other drugs. Whereas the non-homologous glutamate transporters mediate chloride conductance, in the eukaryotic NSS chloride is transported together with the neurotransmitter. In contrast, transport by the bacterial NSS family members LeuT, Tyt1 and TnaT is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17704762
DOI: 10.1038/nature06133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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