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Genetic analysis of DNA repair in the hyperthermophilic archaeon, Thermococcus kodakaraensis.

Genes & genetic systems - 1 Jan 2010

Fujikane Ryosuke, Ishino Sonoko, Ishino Yoshizumi, Forterre Patrick

Abstract excerpt

Extensive biochemical and structural analyses have been performed on the putative DNA repair proteins of hyperthermophilic archaea, in contrast to the few genetic analyses of the genes encoding these proteins. Accordingly, little is known about the repair pathways used by archaeal cells at high temperature. Here, we attempted to disrupt the genes encoding the potential repair proteins in the genome of the...

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PMID: 21178304
DOI: 10.1266/ggs.85.243

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