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Mechanisms and regulation of dsDNA break repair in the Sulfolobus genus of thermophilic archaea

2019-01-01

Abstract excerpt

DNA is constantly subjected to chemical and mechanical damage. The ability to repair the lesions sustained is essential for all life. Double stranded DNA (dsDNA) breaks are especially toxic as both antiparallel strands of DNA are severed. The most high fidelity mechanism available to repair this damage is homologous recombination, a mechanism that uses homology from the sister chromatid to replace any lost informa...

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Literature Corpus work
dcadb484-879d-5fae-a9ec-0a9092c18ca4
DOI
10.17863/cam.37526
Open publication

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