Article
Systems level insights into the stress response to UV radiation in the halophilic archaeon Halobacterium NRC-1.
Genome research - 1 Jun 2004
Baliga Nitin S, Bjork Sarah J, Bonneau Richard, Pan Min, Iloanusi Chika, Kottemann Molly C H, Hood Leroy, DiRuggiero Jocelyne
Abstract excerpt
We report a remarkably high UV-radiation resistance in the extremely halophilic archaeon Halobacterium NRC-1 withstanding up to 110 J/m2 with no loss of viability. Gene knockout analysis in two putative photolyase-like genes (phr1 and phr2) implicated only phr2 in photoreactivation. The UV-response was further characterized by analyzing simultaneously, along with gene function and protein interactions inferred...
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