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Article

Extremely radiation-resistant mutants of a halophilic archaeon with increased single-stranded DNA-binding protein (RPA) gene expression.

Radiation research - 1 Oct 2007

DeVeaux Linda C, Müller Jochen A, Smith Jonathon, Petrisko Jill, Wells Douglas P, DasSarma Shiladitya

Abstract excerpt

Extremely halophilic archaea are highly resistant to multiple stressors, including radiation, desiccation and salinity. To study the basis of stress resistance and determine the maximum tolerance to ionizing radiation, we exposed cultures of the model halophile Halobacterium sp. NRC-1 to four cycles of irradiation with high doses of 18-20 MeV electrons. Two independently obtained mutants displayed an LD(50) > 11...

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PMID: 17903038
DOI: 10.1667/RR0935.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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