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Article

Possible function of the second RecJ-like protein in stalled replication fork repair by interacting with Hef.

Scientific reports - 5 Dec 2017

Nagata Mariko, Ishino Sonoko, Yamagami Takeshi, Simons Jan-Robert, Kanai Tamotsu, Atomi Haruyuki, Ishino Yoshizumi

Abstract excerpt

RecJ was originally identified in Escherichia coli and plays an important role in the DNA repair and recombination pathways. Thermococcus kodakarensis, a hyperthermophilic archaeon, has two RecJ-like nucleases. These proteins are designated as GAN (GINS-associated nuclease) and HAN (Hef-associated nuclease), based on the protein they interact with. GAN is probably a counterpart of Cdc45 in the eukaryotic CMG...

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Identifiers

PMID: 29209094
DOI: 10.1038/s41598-017-17306-0
PMCID: PMC5717133

Genes

GAN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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