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Article

Identification of essential and non-essential single-stranded DNA-binding proteins in a model archaeal organism.

Nucleic acids research - 1 Feb 2012

Skowyra Agnieszka, MacNeill Stuart A

Abstract excerpt

Single-stranded DNA-binding proteins (SSBs) play vital roles in all aspects of DNA metabolism in all three domains of life and are characterized by the presence of one or more OB fold ssDNA-binding domains. Here, using the genetically tractable euryarchaeon Haloferax volcanii as a model, we present the first genetic analysis of SSB function in the archaea. We show that genes encoding the OB fold and zinc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21976728
DOI: 10.1093/nar/gkr838
PMCID: PMC3273820

Genes

SSB

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Identification of essential and non-essential single-stranded DNA-binding proteins in a model archaeal organism.PMID 21976728Read ↗

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