Defective elongation of fatty acids in a recessive 25-hydroxycholesterol-resistant mutant cell line.

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Article

Defective elongation of fatty acids in a recessive 25-hydroxycholesterol-resistant mutant cell line.

The Journal of biological chemistry - 25 Aug 1990

Panini S R, Lutz R J, Wenger L, Miyake J, Leonard S, Andalibi A, Lusis A J, Sinensky M

Abstract excerpt

The Chinese hamster ovary recessive mutant, crB, has been selected for its resistance to the cytotoxic effects of 25-hydroxycholesterol in sterol-free media (Sinensky, M., Logel, J., and Torget, R. (1982) J. Cell. Physiol. 113, 314-319). Growth of crB in a chemically defined lipid-poor medium is...

Topics

Acetates
Animals
Aphidicolin
Cell Division
Cell Line
Cricetinae
Cricetulus
Diterpenes
Drug Resistance
Enzyme Repression
Fatty Acids
Female
Genes, Recessive
Hydroxycholesterols
Hydroxymethylglutaryl CoA Reductases
Inositol
Kinetics
Mutation

Source

Open in PubMed

Identifiers

PMID: 2117604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2117604-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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