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Article

Defective elongation of fatty acids in a recessive 25-hydroxycholesterol-resistant mutant cell line.

The Journal of biological chemistry - 25 Aug 1990

Panini S R, Lutz R J, Wenger L, Miyake J, Leonard S, Andalibi A, Lusis A J, Sinensky M

Abstract excerpt

The Chinese hamster ovary recessive mutant, crB, has been selected for its resistance to the cytotoxic effects of 25-hydroxycholesterol in sterol-free media (Sinensky, M., Logel, J., and Torget, R. (1982) J. Cell. Physiol. 113, 314-319). Growth of crB in a chemically defined lipid-poor medium is very slow and is enhanced by a mixture of saturated and unsaturated fatty acids. Incorporation of [3H]acetate into...

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PMID: 2117604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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