Article
No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression.
Psychiatry research - 30 Jun 2011
Serretti Alessandro, Chiesa Alberto, Calati Raffaella, Massat Isabelle, Linotte Sylvie, Kasper Siegfried, Lecrubier Yves, Fink Martin, Antonijevic Irina, Forray Carlos, Snyder Lenore, Bollen Joseph, Zohar Joseph, De Ronchi Diana, Souery Daniel, Mendlewicz Julien
Abstract excerpt
In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.
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