Article
Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2010
Horstmann Sonja, Lucae Susanne, Menke Andreas, Hennings Johannes M, Ising Marcus, Roeske Darina, Müller-Myhsok Bertram, Holsboer Florian, Binder Elisabeth B
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in the FKBP5, GRIK4, and HTR2A genes have been shown to be associated with response to citalopram treatment in the STAR(*)D sample, but only associations with FKBP5 have so far been tested in the Munich Antidepressant Response Signature (MARS) project. Respo...
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