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Article

Influence of COX-2 and OXTR polymorphisms on treatment outcome in treatment resistant depression.

Neuroscience letters - 10 May 2012

Mendlewicz Julien, Crisafulli Concetta, Calati Raffaella, Kocabas Neslihan Aygun, Massat Isabelle, Linotte Sylvie, Kasper Siegfried, Fink Martin, Sidoti Antonina, Scantamburlo Gabrielle, Ansseau Marc, Antonijevic Irina, Forray Carlos, Snyder Lenore, Bollen Joseph, Montgomery Stuart, Zohar Joseph, Souery Daniel, Serretti Alessandro

Abstract excerpt

Inflammatory pathways play a crucial role in the pathomechanisms of antidepressant efficacy. The aim of this study was to investigate whether a set of single nucleotide polymorphisms (SNPs) within cyclooxygenase-2 (COX-2, rs5275 and rs20417) and oxytocin receptor (OXTR, rs53576 and rs2254298) gen...

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Share to Cyclooxygenase 2
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Share to Polymorphism, Single Nucleotide
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Share to Receptors, Oxytocin
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Source

Identifiers

PMID: 22487732
DOI: 10.1016/j.neulet.2012.03.063

Genes

OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22487732-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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