Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of genetic variations in the STAT4 and IRF7/KIAA1542 regions with systemic lupus erythematosus in a Northern Han Chinese population.

Human immunology - 1 Mar 2011

Li Ping, Cao Chunwei, Luan Haixia, Li Chaohua, Hu Chaojun, Zhang Shulan, Zeng Xiaofeng, Zhang Fengchun, Zeng Changqing, Li Yongzhe

Abstract excerpt

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease with complex genetic inheritance. Genome-wide association studies have identified SLE susceptibility variations at the IRF7/KIAA1542 locus and with STAT4 gene in European populations. We decided to investigate the association of single-nucleotide polymorphisms (SNPs) in the IRF7/KIAA1542 region (rs4963128, rs2246614, and rs702966) and in STAT4...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis
Share to Autoantibodies
Share to China
Share to Genome-Wide Association Study
Share to Lupus Erythematosus, Systemic
Share to Lupus Nephritis
Share to Signal Transduction
Share to STAT4 Transcription Factor

Source

Identifiers

PMID: 21167895
DOI: 10.1016/j.humimm.2010.12.011

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of genetic variations in the STAT4 and IRF7/KIAA1542 regions with systemic lupus erythematosus in a Northern Han Chinese population.PMID 21167895Read ↗

Association of a functional IRF7 variant with systemic lupus erythematosus.Semantic proximity Read ↗

Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population.Semantic proximity Read ↗

No evidence for a genetic association of IRF4 with systemic lupus erythematosus in a Chinese population.Semantic proximity Read ↗

Variants in the interferon regulatory factor 5 gene confer genetic risk for systemic lupus erythematosus in a Han Chinese population.Semantic proximity Read ↗

Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients.Semantic proximity Read ↗

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.Semantic proximity Read ↗

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.Semantic proximity Read ↗

Association of functional polymorphisms in interferon regulatory factor 2 (IRF2) with susceptibility to systemic lupus erythematosus: a case-control association study.Semantic proximity Read ↗

A meta-analysis of the association of IRF5 polymorphism with systemic lupus erythematosus.Semantic proximity Read ↗

Association of IRF5, STAT4 and BLK with systemic lupus erythematosus and other rheumatic diseases.Semantic proximity Read ↗

Novel polymorphism of IFI44L associated with the susceptibility and clinical characteristics of systemic lupus erythematosus in a Chinese population.Semantic proximity Read ↗

Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.