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Article

CTLA-4 exon 1 +49 polymorphism alone and in a haplotype with -318 promoter polymorphism may confer susceptibility to chronic HBV infection in Chinese Han patients.

Molecular biology reports - 1 Nov 2011

Duan Shaoqiong, Zhang Guoyu, Han Qunying, Li Zhu, Liu Zhengwen, Chen Jinghong, Lv Yi, Li Na, Wang Yawen, Li Man, Lou Sai, Yang Mingbo, Zhu Qianqian, Xing Fanfan

Abstract excerpt

Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) plays a pivotal role in regulating T cell activation, which is believably critical for the outcome of hepatitis B virus (HBV) infection. The expression and function of CTLA-4 may be affected by gene polymorphisms. This study investigated the in...

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Identifiers

PMID: 21161390
DOI: 10.1007/s11033-010-0660-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21161390-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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