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Article

Correlations of CTLA-4 gene polymorphisms and hepatitis C chronic infection.

Liver international : official journal of the International Association for the Study of the Liver - 1 May 2012

Danilovic Debora L S, Mendes-Correa Maria C, Lima Erika U, Zambrini Heverton, K Barros Raffaelle, Marui Suemi

Abstract excerpt

BACKGROUND: Cytotoxic T lymphocyte-associated factor 4 (CTLA-4) functions as a negative regulator of T cell-mediated immune response. Molecular changes associated to CTLA-4 gene polymorphisms could reduce its ability to suppress and control lymphocyte proliferation. AIMS: To evaluate the frequency of CTLA-4 gene polymorphisms in chronic hepatitis C virus (HCV) infected patients and correlate to clinical and...

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Share to CTLA-4 Antigen
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C, Chronic

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 22136395
DOI: 10.1111/j.1478-3231.2011.02694.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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