Article
[Association of CTLA4 gene +49G/A polymorphism with HBV infection and HBV-related hepatocellular carcinoma in Hunan Han population].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Aug 2010
Liu Gang, Lu Guang-xiu
Abstract excerpt
OBJECTIVE: To investigate the relationship between CTLA4 +49G/A SNP polymorphism and the susceptibility to hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). METHODS: CTLA4+49G/A single nucleotide polymorphism (SNP) was analyzed by DNA sequencing in 165 control subjects, 155 patients...
Topics
- Adult
- Asian People
- CTLA-4 Antigen
- Carcinoma, Hepatocellular
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Hepatitis B
- Hepatitis B Surface Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
