Article
[Association of CTLA4 gene +49G/A polymorphism with HBV infection and HBV-related hepatocellular carcinoma in Hunan Han population].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Aug 2010
Liu Gang, Lu Guang-xiu
Abstract excerpt
OBJECTIVE: To investigate the relationship between CTLA4 +49G/A SNP polymorphism and the susceptibility to hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). METHODS: CTLA4+49G/A single nucleotide polymorphism (SNP) was analyzed by DNA sequencing in 165 control subjects, 155 patients with chronic hepatitis B (CHB) and 149 HCC patients. Serum HBsAg, HBeAg and AFP levels were measured in all the...
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