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Article

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1 Aug 1990

Abstract excerpt

Nuclear extracts derived from HeLa and Drosophila melanogaster KC cell lines have been found to correct single base-base mispairs within open circular DNA heteroduplexes containing a strand-specific, site-specific incision located 808 base pairs from the mismatch. Correction in both extract systems is strand specific, being highly biased to the incised DNA strand. Different mispairs within a homologous set of...

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PMID: 2116007
DOI: 10.1073/pnas.87.15.5837

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