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Article

Thyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC).

The Journal of clinical endocrinology and metabolism - 1 Mar 2011

Jazdzewski Krystian, Boguslawska Joanna, Jendrzejewski Jaroslaw, Liyanarachchi Sandya, Pachucki Janusz, Wardyn Kazimierz A, Nauman Alicja, de la Chapelle Albert

Abstract excerpt

CONTEXT: Loss of the thyroid hormone receptor is common in tumors. In mouse models, a truncated THRB gene leads to thyroid cancer. Previously, we observed up-regulation of the expression of eight microRNAs (miRs) in papillary thyroid carcinoma (PTC) tumors. OBJECTIVE: Our objective was to determi...

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Source

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Identifiers

PMID: 21159845
DOI: 10.1210/jc.2010-1594
PMCID: PMC3047217

Genes

THRB
APP
DIO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21159845-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Thyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC).PMID 21159845Read ↗

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