Article
New global analysis of the microRNA transcriptome of primary tumors and lymph node metastases of papillary thyroid cancer.
BMC genomics - 21 Oct 2015
Saiselet Manuel, Gacquer David, Spinette Alex, Craciun Ligia, Decaussin-Petrucci Myriam, Andry Guy, Detours Vincent, Maenhaut Carine
Abstract excerpt
BACKGROUND: Papillary Thyroid Cancer (PTC) is the most prevalent type of endocrine cancer. Its incidence has rapidly increased in recent decades but little is known regarding its complete microRNA transcriptome (miRNome). In addition, there is a need for molecular biomarkers allowing improved PTC diagnosis. METHODS: We performed small RNA deep-sequencing of 3 PTC, their matching normal tissues and lymph node...
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