Structure-function analysis of the human interferon gamma. The COOH terminus is not essential for functional activity.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Structure-function analysis of the human interferon gamma. The COOH terminus is not essential for functional activity.

The Journal of biological chemistry - 5 Aug 1990

Luk S K, Jay E, Jay F T

Abstract excerpt

The structure-function relationships for the human interferon gamma (HuIFN-gamma) were studied using recombinant variants that had various deletions at the carboxyl terminus. Four COOH-terminal deletion variants were constructed that contained the amino-terminal 122, 117, 111, and 106 amino acid...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Western
Chromosome Deletion
Genetic Variation
Humans
Interferon-gamma
Molecular Sequence Data
Molecular Weight
Mutation
Plasmids
Protein Conformation
Recombinant Proteins
Restriction Mapping

Source

Open in PubMed

Identifiers

PMID: 2115890

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2115890-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics