Article
Mutation in a mitochondrial ribosomal protein causes increased sensitivity to oxygen with decreased longevity in the nematode Caenorhabditis elegans.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2011
Fujii Michihiko, Shikatani Kazuki, Ogura Ken-Ichi, Goshima Yoshio, Ayusawa Dai
Abstract excerpt
Oxygen is essential for animals, but high concentrations of oxygen are toxic to them probably because of an increase in reactive oxygen species (ROS). Many genes are involved in the reactions from which ROS are generated, but not much attention has been focused on them. To identify these genes, w...
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