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Article

Oxidative stress and life span determination in the nematode Caenorhabditis elegans.

Annals of the New York Academy of Sciences - 1 Apr 2002

Honda Yoko, Honda Shuji

Abstract excerpt

The free radical theory of aging proposes that oxidative stress is one of the determinants of an organism's life span. In Caenorhabditis elegans, genetic or environmental changes have been shown to modulate life span. Here we discuss whether changes in the generation and destruction of free radicals are implicated in these life span modulations. Changes in culture oxygen concentrations that are considered to...

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PMID: 11976220
DOI: 10.1111/j.1749-6632.2002.tb02117.x

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