Polymorphisms of miR-146a and susceptibility to ulcerative colitis risk: a case-control study.

doi:10.1080/15257770.2022.2118768

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Article

Polymorphisms of miR-146a and susceptibility to ulcerative colitis risk: a case-control study.

Nucleosides, nucleotides & nucleic acids - 1 Jan 2023

Kolahi Samira Nasiri, Salehi Zivar, Sasani Soheila Talesh, Mashayekhi Farhad, Aminian Keyvan

Abstract excerpt

Considering the role of miR-146a in the control of inflammation, we assessed the importance of two miR-146a polymorphisms (rs2910164 and rs57095329) in the development and severity of ulcerative colitis (UC) in Iran. Genomic DNA of 150 cases with UC and 200 healthy individuals were genotyped using the PCR-RFLP technique. Statistical analyses were performed using Med Calc software. The miR-146a rs2910164 C allele...

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PMID: 36075029
DOI: 10.1080/15257770.2022.2118768

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