Article
Genomic aberrations in lung adenocarcinoma in never smokers.
PloS one - 6 Dec 2010
Job Bastien, Bernheim Alain, Beau-Faller Michèle, Camilleri-Broët Sophie, Girard Philippe, Hofman Paul, Mazières Julien, Toujani Saloua, Lacroix Ludovic, Laffaire Julien, Dessen Philippe, Fouret Pierre
Abstract excerpt
BACKGROUND: Lung cancer in never smokers would rank as the seventh most common cause of cancer death worldwide. METHODS AND FINDINGS: We performed high-resolution array comparative genomic hybridization analysis of lung adenocarcinoma in sixty never smokers and identified fourteen new minimal common regions (MCR) of gain or loss, of which five contained a single gene (MOCS2, NSUN3, KHDRBS2, SNTG1 and ST18). One...
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