Article
Novel Approaches for BAV Aortopathy Prediction-Is There a Need for Cohort Studies and Biomarkers?
Biomolecules - 19 Jul 2018
Girdauskas Evaldas, Petersen Johannes, Neumann Niklas, Naito Shiho, Gross Tatiana, Jagodzinski Annika, Reichenspurner Hermann, Zeller Tanja
Abstract excerpt
Bicuspid aortic valve (BAV) disease is the most common congenital malformation of the human heart with a prevalence of 1⁻2% in the general population. More than half of patients with a BAV present with a dilated proximal aorta (so-called bicuspid aortopathy) which is associated with an enhanced risk of life-threatening aortic complications. Up to now, the pathogenesis of bicuspid aortopathy as well as the risk...
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